Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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Treprostinil (Remodulin) has a mechanism of action that includes:

  1. Blocking aldosterone receptors

  2. Inhibiting cyclooxygenase enzyme

  3. Dilating blood vessels and inhibiting platelet aggregation

  4. Blocking calcium channels

The correct answer is: Dilating blood vessels and inhibiting platelet aggregation

Treprostinil (Remodulin) is a prostacyclin analog that works by stimulating prostacyclin receptors in the blood vessels, leading to vasodilation and inhibition of platelet aggregation. This mechanism is important for treating pulmonary arterial hypertension, as it helps to reduce the resistance in the pulmonary blood vessels, improving blood flow and reducing symptoms. Therefore, options A, B, and D are not correct as they do not involve vasodilation or inhibition of platelet aggregation. Blocking aldosterone receptors (option A) may be used for treating hypertension or heart failure, inhibiting cyclooxygenase enzyme (option B) is a mechanism used in non-steroidal anti-inflammatory drugs, and blocking calcium channels (option D) is a mechanism used in calcium channel blockers for cardiovascular conditions. However, these mechanisms are not involved in the action of Treprostinil (Remodulin). Only

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