Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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What is the mechanism of action for alpha1 blockers?

Increasing norepinephrine production
Reducing sympathetic outflow
Blocking alpha1-adrenergic receptors
Stimulating beta receptors

The correct answer is: Blocking alpha1-adrenergic receptors

Alpha1 blockers are a class of drugs that act by blocking alpha1-adrenergic receptors, which are found in the smooth muscle of blood vessels. These receptors are responsible for causing vasoconstriction, or the narrowing of blood vessels. By blocking these receptors, alpha1 blockers can relax blood vessels and reduce blood pressure. Options A, B, and D are incorrect because they describe actions that do not pertain to alpha1 blockers. Increasing norepinephrine production, reducing sympathetic outflow, and stimulating beta receptors are actions that would have the opposite effect and increase blood pressure.